@import "https://fonts.googleapis.com/css2?family=Inter:wght@300;400;500;600;700&family=Outfit:wght@400;500;600;700;800&display=swap";.site-header{border-bottom:1px solid var(--border);z-index:50;box-shadow:var(--shadow);background-color:#fff;position:sticky;top:0}.header-container{justify-content:space-between;align-items:center;height:90px;display:flex}.logo-link{color:var(--primary);outline:none;align-items:center;gap:12px;text-decoration:none;display:flex}.header-logo{object-fit:contain;width:auto;height:60px}.logo-text{font-family:var(--font-heading);letter-spacing:-.5px;font-size:1.5rem;font-weight:800;line-height:1}.logo-subtext{color:var(--accent);display:inline-block}.nav-list{gap:32px;list-style:none;display:flex}.nav-link{color:var(--text-body);transition:color var(--transition-fast);padding:8px 0;font-size:1.05rem;font-weight:600;position:relative}.nav-link:after{content:"";background-color:var(--accent);width:0;height:2px;transition:width var(--transition-fast);position:absolute;bottom:0;left:0}.nav-link:hover:after,.nav-link:focus:after,.nav-link.active:after{width:100%}.nav-link:hover,.nav-link:focus,.nav-link.active{color:var(--accent)}.menu-toggle{cursor:pointer;background:0 0;border:none;padding:12px;display:none}.hamburger{background-color:var(--primary);width:24px;height:2px;transition:background-color var(--transition-fast);display:block;position:relative}.hamburger:before,.hamburger:after{content:"";background-color:var(--primary);width:24px;height:2px;transition:transform var(--transition-fast), top var(--transition-fast);position:absolute;left:0}.hamburger:before{top:-8px}.hamburger:after{top:8px}@media (width<=992px){.menu-toggle{display:block}.site-nav{border-bottom:1px solid var(--border);width:100%;max-height:0;transition:max-height var(--transition-normal);background-color:#fff;position:absolute;top:90px;left:0;overflow:hidden;box-shadow:0 10px 15px -3px #0000000d}.site-nav.is-open{max-height:400px}.nav-list{flex-direction:column;align-items:center;gap:16px;padding:24px}.nav-link{text-align:center;width:100%;padding:12px 0;display:block}.menu-toggle[aria-expanded=true] .hamburger{background-color:#0000}.menu-toggle[aria-expanded=true] .hamburger:before{top:0;transform:rotate(45deg)}.menu-toggle[aria-expanded=true] .hamburger:after{top:0;transform:rotate(-45deg)}}@media (prefers-color-scheme:dark){.site-header,.site-nav{background-color:#1e293b}.hamburger,.hamburger:before,.hamburger:after{background-color:#f8fafc}}.site-footer{background-color:var(--primary);color:#f8fafc;border-top:4px solid var(--accent);margin-top:auto;padding:60px 0 0}.footer-container{grid-template-columns:1.5fr 2fr;gap:48px;padding-bottom:48px;display:grid}.footer-info{flex-direction:column;gap:16px;display:flex}.footer-logo-link{color:#fff;outline:none;align-items:center;gap:12px;text-decoration:none;display:flex}.footer-logo{background-color:#fff;border-radius:4px;width:auto;height:50px;padding:2px}.footer-logo-text{font-family:var(--font-heading);letter-spacing:-.5px;font-size:1.35rem;font-weight:800}.footer-logo-subtext{color:#ffaa6b}.footer-tagline{color:#cbd5e1;max-width:400px;font-size:.95rem;line-height:1.6}.footer-links-container{grid-template-columns:1fr 1fr;gap:32px;display:grid}.footer-heading{color:#fff;text-transform:uppercase;letter-spacing:1px;margin-bottom:20px;font-size:1.15rem;font-weight:700}.footer-links{flex-direction:column;gap:12px;list-style:none;display:flex}.footer-links a{color:#cbd5e1;transition:color var(--transition-fast);font-size:.95rem;text-decoration:none}.footer-links a:hover,.footer-links a:focus{color:#ffaa6b;text-decoration:underline}.footer-bottom{background-color:#0b1828;border-top:1px solid #ffffff14;padding:24px 0}.footer-bottom-container{color:#94a3b8;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:16px;font-size:.85rem;display:flex}@media (width<=768px){.footer-container{grid-template-columns:1fr;gap:36px}.footer-links-container{grid-template-columns:1fr;gap:28px}.footer-bottom-container{text-align:center;flex-direction:column}}.home-page{flex-grow:1}.hero-section{border-bottom:1px solid var(--border);background:linear-gradient(135deg,#152a4508 0%,#be510308 100%);padding:80px 0}.hero-container{grid-template-columns:1.2fr 1fr;align-items:center;gap:48px;display:grid}.hero-content{text-align:left}.hero-headline{color:var(--primary);margin-bottom:24px;font-size:3.25rem;line-height:1.15}.highlight-text{color:var(--accent)}.hero-subheadline{color:var(--primary-light);margin-bottom:20px;font-size:1.35rem;font-weight:600;line-height:1.4}.hero-message{color:var(--text-body);max-width:600px;margin-bottom:32px;font-size:1.1rem}.hero-actions{gap:16px;display:flex}.hero-image-container{justify-content:center;display:flex;position:relative}.hero-image{object-fit:cover;width:100%;max-width:500px;height:450px;box-shadow:var(--shadow-hover);border:1px solid var(--border);border-radius:12px}.stats-section{background-color:var(--bg-card);padding:80px 0}.stats-header{text-align:center;max-width:800px;margin:0 auto 50px}.section-title{color:var(--primary);margin-bottom:16px}.section-title:after{content:"";background-color:var(--accent);border-radius:2px;width:60px;height:4px;margin:12px auto 0;display:block}.stats-intro{color:var(--text-muted);font-size:1.15rem}.stats-grid{grid-template-columns:repeat(auto-fit,minmax(240px,1fr));gap:30px;display:grid}.stat-card,.stat-cardHighlight{background-color:var(--bg-page);box-shadow:var(--shadow);border:1px solid var(--border);transition:transform var(--transition-fast), box-shadow var(--transition-fast);text-align:center;border-radius:8px;padding:40px 24px}.stat-cardHighlight{border-color:var(--accent);background-color:#be510308}.stat-card:hover,.stat-cardHighlight:hover{box-shadow:var(--shadow-hover);transform:translateY(-5px)}.stat-number{font-family:var(--font-heading);color:var(--accent);margin-bottom:12px;font-size:2.75rem;font-weight:800;line-height:1;display:block}.stat-card .stat-number{color:var(--primary)}.stat-cardHighlight .stat-number{color:var(--accent)}.stat-text{color:var(--text-body);font-size:1rem;font-weight:500}.cta-section{background-color:var(--primary);color:#fff;text-align:center;padding:60px 0}.cta-container{flex-direction:column;align-items:center;gap:20px;max-width:700px;display:flex}.cta-section h2{color:#fff}.cta-section p{color:#cbd5e1;font-size:1.15rem}.cta-section .btn-primary{background-color:var(--accent);color:#fff;border:none}.cta-section .btn-primary:hover{background-color:var(--accent-light)}@media (width<=992px){.hero-container{text-align:center;grid-template-columns:1fr;gap:36px}.hero-content{text-align:center}.hero-message{margin-left:auto;margin-right:auto}.hero-actions{justify-content:center}.hero-image{max-height:350px}}@media (width<=576px){.hero-headline{font-size:2.25rem}.hero-actions{flex-direction:column;width:100%}.hero-actions .btn{width:100%}}@media (prefers-color-scheme:dark){.hero-section{background:linear-gradient(135deg,#58a6ff0d 0%,#ff88380d 100%)}.stat-card{background-color:#1e293b}.stat-cardHighlight{border-color:var(--accent);background-color:#1e293b}.stat-card .stat-number{color:var(--primary)}}.science-page{flex-grow:1;padding:60px 0}.science-content{grid-template-columns:1.2fr .8fr;align-items:start;gap:40px;display:grid}.science-card{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);border-radius:8px;padding:40px}.science-card h2{color:var(--primary);margin-bottom:24px;font-size:1.75rem}.science-diagram-placeholder{flex-direction:column;gap:16px;display:flex}.placeholder-graphic{background-color:var(--bg-card);border:2px dashed var(--border);height:250px;color:var(--text-muted);border-radius:8px;flex-direction:column;justify-content:center;align-items:center;gap:16px;display:flex}.graphic-icon{color:var(--accent);font-size:3rem}.graphic-caption{color:var(--text-muted);text-align:center;font-size:.9rem;line-height:1.4}@media (width<=768px){.science-content{grid-template-columns:1fr}}.about-page{flex-grow:1;padding:60px 0}.scientific-origin{margin-bottom:80px}.origin-card{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);border-radius:8px;grid-template-columns:1.5fr 1fr;align-items:center;gap:40px;padding:40px;display:grid}.origin-content{text-align:left}.origin-content h2{color:var(--primary);margin-bottom:16px;font-size:1.75rem}.origin-content p{color:var(--text-body);margin-bottom:24px;font-size:1.15rem;line-height:1.7}.pks-placeholder-info{background-color:var(--bg-page);border-left:4px solid var(--accent);border-radius:6px;padding:20px}.pks-placeholder-info h3{color:var(--primary);margin-bottom:10px;font-size:1.15rem}.pks-placeholder-info ul{padding:0;list-style-type:none}.pks-placeholder-info li{color:var(--text-body);margin-bottom:8px;padding-left:20px;font-size:.95rem;position:relative}.pks-placeholder-info li:before{content:"•";color:var(--accent);font-size:1.25rem;font-weight:700;position:absolute;top:-2px;left:0}.origin-media{flex-direction:column;align-items:center;display:flex}.origin-photo{object-fit:cover;width:100%;max-width:250px;height:250px;box-shadow:var(--shadow);border:3px solid var(--border);border-radius:50%}.photo-label{color:var(--text-muted);margin-top:12px;font-size:.9rem;font-weight:600}.team-section{margin-bottom:60px}.team-section .section-title{color:var(--primary);text-align:center;margin-bottom:30px}.team-section .section-title:after{content:"";background-color:var(--accent);width:50px;height:3px;margin:10px auto 0;display:block}.team-grid{grid-template-columns:repeat(auto-fit,minmax(280px,1fr));gap:30px;display:grid}.justify-center{grid-template-columns:repeat(2,minmax(280px,400px));justify-content:center}.team-card{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);transition:transform var(--transition-fast), box-shadow var(--transition-fast);text-align:center;border-radius:8px;flex-direction:column;display:flex;overflow:hidden}.team-card:hover{box-shadow:var(--shadow-hover);transform:translateY(-5px)}.team-photo{object-fit:cover;border-bottom:1px solid var(--border);background-color:#f1f5f9;width:100%;height:250px}.team-info{text-align:left;flex-direction:column;flex-grow:1;gap:8px;padding:24px;display:flex}.team-info h3{color:var(--primary);margin:0;font-size:1.25rem}.team-role{color:var(--accent);text-transform:uppercase;letter-spacing:.5px;font-size:.95rem;font-weight:600}.team-bg{color:var(--text-body);font-size:.95rem;line-height:1.4}@media (width<=992px){.origin-card{grid-template-columns:1fr;gap:30px}.origin-media{order:-1}}@media (width<=768px){.justify-center{grid-template-columns:1fr}}.clinical-page{flex-grow:1;padding:60px 0}.clinical-overview{flex-direction:column;gap:40px;display:flex}.clinical-card{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);text-align:left;border-radius:8px;padding:40px}.clinical-card h2{color:var(--primary);margin-bottom:20px;font-size:1.75rem}.lorem-ipsum-text{color:var(--text-body);font-size:1.1rem;font-style:italic;line-height:1.8}.pipeline-table-container{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);text-align:left;border-radius:8px;padding:40px}.pipeline-table-container h2{color:var(--primary);margin-bottom:24px;font-size:1.75rem}.table-responsive{-webkit-overflow-scrolling:touch;width:100%;overflow-x:auto}.pipeline-table{border-collapse:collapse;text-align:left;width:100%;margin-top:10px;font-size:1.05rem}.pipeline-table th,.pipeline-table td{border-bottom:1px solid var(--border);padding:16px 20px}.pipeline-table th{color:var(--primary);font-weight:700;font-family:var(--font-heading);background-color:#152a450a}.pipeline-table tbody tr:hover{background-color:#152a4505}.badge{text-transform:uppercase;letter-spacing:.5px;border-radius:4px;padding:4px 10px;font-size:.85rem;font-weight:700;display:inline-block}.badge-active{color:var(--accent);background-color:#be51031a;border:1px solid #be51034d}.badge-prep{color:var(--primary);background-color:#152a451a;border:1px solid #152a454d}@media (prefers-color-scheme:dark){.pipeline-table th{color:var(--primary-light);background-color:#ffffff0d}.pipeline-table tbody tr:hover{background-color:#ffffff05}}.contact-page{flex-grow:1;padding:60px 0}.page-container{max-width:1100px}.page-header{text-align:center;margin-bottom:50px}.page-title{color:var(--primary);margin-bottom:8px}.page-subtitle{color:var(--text-muted);font-size:1.2rem}.contact-grid{grid-template-columns:1fr 1.5fr;align-items:start;gap:40px;display:grid}.info-card,.form-card{background-color:var(--bg-card);box-shadow:var(--shadow);border:1px solid var(--border);text-align:left;border-radius:8px;padding:40px}.info-card h2,.form-card h2{color:var(--primary);margin-bottom:24px;font-size:1.75rem}.info-card p{color:var(--text-body);margin-bottom:24px;font-size:1.05rem}.info-details{flex-direction:column;gap:24px;display:flex}.info-item{align-items:flex-start;gap:16px;display:flex}.info-icon{color:var(--accent);background-color:#be510314;border-radius:50%;flex-shrink:0;justify-content:center;align-items:center;width:40px;height:40px;font-size:1.5rem;display:flex}.info-item strong{color:var(--primary);font-size:1rem;display:block}.info-item a{color:var(--accent);text-decoration:none}.info-item a:hover{text-decoration:underline}.warning-card{border-left:4px solid var(--accent);background-color:#be510305;margin-top:30px}.warning-card h3{color:var(--accent);margin-bottom:12px;font-size:1.2rem}.warning-card p{color:var(--text-body);margin:0;font-size:.95rem;line-height:1.6}.required{color:#dc2626}.form-row{grid-template-columns:1fr 1fr;gap:20px;display:grid}.textarea-control{resize:vertical}.turnstile-container{justify-content:flex-start;margin:20px 0;display:flex}.btn-submit{width:100%;padding:14px 20px;font-size:1.1rem}.alert{border-radius:6px;margin-bottom:24px;padding:16px 20px;font-size:1rem}.alert-success{color:#166534;background-color:#f0fdf4;border:1px solid #bbf7d0;flex-direction:column;align-items:flex-start;gap:16px;display:flex}.alert-error{color:#991b1b;background-color:#fef2f2;border:1px solid #fecaca}.btn-sm{padding:6px 12px;font-size:.85rem}@media (width<=992px){.contact-grid{grid-template-columns:1fr}}@media (width<=576px){.form-row{grid-template-columns:1fr;gap:0}}:root{--color-navy:#152a45;--color-burnt-orange:#be5103;--color-ivory:ivory;--primary:var(--color-navy);--primary-light:#233f63;--accent:var(--color-burnt-orange);--accent-light:#df6107;--bg-page:var(--color-ivory);--bg-card:#fff;--text-primary:#152a45;--text-body:#2d3748;--text-muted:#5a6a80;--border:#152a4526;--shadow:0 4px 6px -1px #0000000d, 0 2px 4px -1px #00000008;--shadow-hover:0 10px 15px -3px #00000014, 0 4px 6px -2px #0000000a;--focus-ring:0 0 0 3px #be510366;--font-sans:"Inter", system-ui, -apple-system, sans-serif;--font-heading:"Outfit", system-ui, -apple-system, sans-serif;--transition-fast:.15s ease;--transition-normal:.25s ease;--max-width:1200px}@media (prefers-color-scheme:dark){:root{--primary:#58a6ff;--primary-light:#79c0ff;--accent:#ff8838;--accent-light:#ffa46b;--bg-page:#0f172a;--bg-card:#1e293b;--text-primary:#f8fafc;--text-body:#cbd5e1;--text-muted:#94a3b8;--border:#ffffff1a;--shadow:0 4px 6px -1px #0003;--shadow-hover:0 10px 15px -3px #0000004d;--focus-ring:0 0 0 3px #ff883880}}*{box-sizing:border-box;margin:0;padding:0}body{font-family:var(--font-sans);background-color:var(--bg-page);color:var(--text-body);-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;font-size:1.125rem;line-height:1.6}.skip-link{background:var(--accent);color:#fff;z-index:100;padding:8px;text-decoration:none;transition:top .2s;position:absolute;top:-40px;left:0}.skip-link:focus{top:0}#root{flex-direction:column;min-height:100vh;display:flex}.container{width:100%;max-width:var(--max-width);margin:0 auto;padding:0 1.5rem}h1,h2,h3,h4{font-family:var(--font-heading);color:var(--text-primary);font-weight:700;line-height:1.25}h1{margin-bottom:1.5rem;font-size:3rem}h2{margin-bottom:1.25rem;font-size:2rem;position:relative}h3{margin-bottom:1rem;font-size:1.5rem}.sr-only{clip:rect(0, 0, 0, 0);border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}.btn{cursor:pointer;transition:all var(--transition-fast);font-size:1rem;font-weight:600;font-family:var(--font-sans);border:2px solid #0000;border-radius:6px;justify-content:center;align-items:center;padding:.75rem 1.5rem;text-decoration:none;display:inline-flex}.btn-primary{background-color:var(--accent);color:#fff}.btn-primary:hover,.btn-primary:focus{background-color:var(--accent-light);transform:translateY(-1px)}.btn-secondary{color:var(--text-primary);border-color:var(--primary);background-color:#0000}.btn-secondary:hover,.btn-secondary:focus{background-color:var(--primary);color:#fff;transform:translateY(-1px)}.btn:focus-visible,a:focus-visible,button:focus-visible,input:focus-visible,select:focus-visible,textarea:focus-visible{box-shadow:var(--focus-ring);outline:none}.form-group{text-align:left;margin-bottom:1.5rem}.form-label{color:var(--text-primary);margin-bottom:.5rem;font-weight:600;display:block}.form-control{width:100%;font-size:1rem;font-family:var(--font-sans);border:1px solid var(--border);background-color:var(--bg-card);color:var(--text-body);transition:border-color var(--transition-fast);border-radius:6px;padding:.75rem 1rem}.form-control:focus{border-color:var(--accent);outline:none}.honeypot-field{visibility:hidden!important;display:none!important}@keyframes fadeIn{0%{opacity:0;transform:translateY(10px)}to{opacity:1;transform:translateY(0)}}.animate-fade-in{animation:fadeIn var(--transition-normal) forwards}nav a{color:var(--text-body);transition:color var(--transition-fast);font-weight:500;text-decoration:none}nav a:hover,nav a:focus,nav a.active{color:var(--accent)}@media (width<=768px){h1{font-size:2.25rem}h2{font-size:1.75rem}body{font-size:1rem}}